In 1953, James Watson and Francis Crick discovered their double helix model of DNA. However, there remains the question how could DNA double helix made up of only four different nucleotides determine the composition of protein polypeptide chain composed of twenty different amino acids?
In 1961 Marshall Nirenberg discovered the first tripret, a codon sequence of three DNA bases that codes for one of the twenty different amino acids. Then, in five years after his discovory, the entire codon table was completed.
DNA: The secret of life by James D. Watson, A. Berry, Knopf (ISBN: 978-0375415463)
Allostery: an illustrated definition for the ‘second secret of life’ by A. W. Fenton, in Trends in Biochemical Sciences, 33(9) 420-425 (2008)
Is allostery an intrinsic property of all dynamic proteins? by K. Gunasekaran, B. Ma, R. Nussinov, in PROTEINS: Structure, Function, and Bioinfomatics, 57(3) 433-443 (2004)
The ensemble nature of allostery by Hesam N. Motlagh, James O. Wrabl, Jing Li, Vincent J. Hilser, Nature 508, 331-339 (2014)
Molecular mechanism of allostery: MWC or KNF model? – Approach by theoretical model calculation by K. Okazaki and Shoji Takada, in Seibutsu Butsuri 49(3) 132-134, (2009)
A unified view of “how allostery works” by Chung-Jung Tsai, Ruth Nussinov, in PLoS Comput. Biol. 10(2): e1003394 (2014)
Hidden dynamic allostery in a PDZ domain by C.M. Petit et al. in PNAS (2009) 106: 18249-18254.
Theory of structural changes in proteins: equilibrium fluctuation and linear response theory by M. Ikeguchi and A. Kidera in Seibutsu Butsuri (2006) 46(5) 275-278
Protein allostery and sequence design principle by Shoji Takada, in Seibutsu Butsuri, 52(3) 150-151 (2012)
Energy transport network in proteins by Takahisa Yamato, in Seibutsu Butsuri, 60(2) 94-97 (2020)
Through bonds or contacs? Mapping protein vibrational energy transfer using non-canonical amino acids by Erhan Deniz et al., in Nature Communications 12: 3284 (2021)